St. Louis is a diverse Midwest commercial market with strengths in logistics, healthcare (Barnes-Jewish/Washington University), financial services, and manufacturing. Affordable occupancy costs relative to coastal markets drive corporate consolidations into the area.
By Angel Campa, Founder · Updated March 2026
Commercial Space
60M sq ft
Avg Office Rent
$18–$28/sq ft
Vacancy Rate
20%
Avg Lease Term
5–10 years
St. Louis industrial leases are NNN. Office is Modified Gross or FSG in the CBD. Healthcare campus leases are specialized. The market's affordability means TI packages are modest.
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